Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1808554 | 0.78 | DRD2 (0.54) | DRD2ACHE | |
| SCHEMBL7978255 | 0.78 | CARM1 (0.51) | HTT | |
| SCHEMBL7979644 | 0.77 | DRD2 (0.50) | KDM1ADRD2DRD3LMNATP53 | |
| SCHEMBL7966072 | 0.77 | DRD3 (0.56) | KDM1ADRD2DRD3LMNAHTT | |
| SCHEMBL6617262 | 0.76 | SIGMAR1 (0.48) | — | |
| SCHEMBL23164620 | 0.75 | HTR1A (0.67) | HTR1A | |
| SCHEMBL12332512 | 0.75 | HTR1A (0.67) | HTR1A | |
| SCHEMBL7976319 | 0.75 | KCNA3 (0.54) | KDM1ADRD2DRD3ACHE | |
| SCHEMBL31172358 | 0.75 | KDM1A (0.55) | KDM1ADRD3ACHEHTR1A | |
| SCHEMBL9733689 | 0.74 | DRD2 (0.84) | ALDH1A1DRD2DRD3LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |