Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.55 |
| ▸ | HRH2 | P25021 | 10/20 | 0.55 |
| ▸ | HRH1 | P35367 | 10/20 | 0.55 |
| ▸ | MMP3 | P08254 | 5/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447851 | 0.94 | ALDH1A1 (0.53) | MMP2HRH3HRH2HRH1MMP3 | |
| SCHEMBL5624212 | 0.92 | MMP2 (0.60) | MMP2HRH3HRH2HRH1MMP3 | |
| SCHEMBL6709103 | 0.91 | MMP3 (0.59) | MMP2HRH3HRH2HRH1MMP3 | |
| SCHEMBL26602050 | 0.86 | MMP3 (0.66) | MMP2HRH3HRH2HRH1MMP3 | |
| SCHEMBL1714609 | 0.86 | HRH3 (0.54) | MMP2HRH3HRH2HRH1MMP3 | |
| SCHEMBL16841044 | 0.84 | HDAC1 (0.67) | MMP2HRH3HRH2HRH1MMP3 | |
| SCHEMBL18079151 | 0.84 | HDAC1 (0.67) | MMP2HRH3HRH2HRH1MMP3 | |
| SCHEMBL29444063 | 0.84 | HDAC1 (0.67) | MMP2HRH3HRH2HRH1MMP3 | |
| SCHEMBL8748087 | 0.84 | HRH3 (0.56) | MMP2HRH3HRH2HRH1MMP3 | |
| SCHEMBL5096555 | 0.82 | MMP2 (0.67) | MMP2HRH3HRH2HRH1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130190504-A1 | Functionalized Polymers Using Protected Thiols | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2013-07-25 | — | — | US | disclosed |
| US-8283438-B2 | Functionalized polymers using protected thiols | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-10-09 | — | — | US | disclosed |
| US-8283438-B2 | Functionalized polymers using protected thiols | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-10-09 | — | — | US | disclosed |
| US-20110077407-A1 | Functionalized Polymers Using Protected Thiols | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2011-03-31 | — | — | US | disclosed |
| US-20110077407-A1 | Functionalized Polymers Using Protected Thiols | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2011-03-31 | — | — | US | disclosed |
| US-7847019-B2 | Functionalized polymers using protected thiols | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2010-12-07 | — | — | US | disclosed |
| US-7847019-B2 | Functionalized polymers using protected thiols | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2010-12-07 | — | — | US | disclosed |
| US-20090176941-A1 | Functionalized Polymers Using Protected Thiols | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2009-07-09 | — | — | US | disclosed |
| US-20090176941-A1 | Functionalized Polymers Using Protected Thiols | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2009-07-09 | — | — | US | disclosed |
| WO-2009052148-A1 | FUNCTIONALIZED POLYMERS USING PROTECTED THIOLS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2009-04-23 | — | — | WO | disclosed |
| WO-2001066534-A2 | CYCLIC AND BICYCLIC DIAMINO HISTAMINE-3 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077407-A1 | Functionalized Polymers Using Protected Thiols | TST, GNE, MGMT | MMP2 3475/4885HRH3 4789/4885HRH2 4821/4885 |
| US-20130190504-A1 | Functionalized Polymers Using Protected Thiols | TST, GNE, MGMT | MMP2 3475/4885HRH3 4789/4885HRH2 4821/4885 |
| US-20090176941-A1 | Functionalized Polymers Using Protected Thiols | TST, GNE, MGMT | MMP2 3475/4885HRH3 4789/4885HRH2 4821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.