Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PTAFR | P25105 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7978632 | 0.88 | MAPT (0.43) | MAPTALOX15HSD17B10ALDH1A1PTAFR | |
| SCHEMBL7980204 | 0.81 | PTAFR (0.45) | PTAFRHPGDHTTGRIN2BGRIN1 | |
| SCHEMBL7966043 | 0.81 | PTAFR (0.45) | PTAFRHPGDHTTGRIN2BGRIN1 | |
| SCHEMBL7980157 | 0.78 | PTAFR (0.42) | MAPTALDH1A1PTAFRHPGDKMT2A | |
| SCHEMBL7982543 | 0.75 | ALDH1A1 (0.43) | MAPTHSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL7982544 | 0.75 | ALDH1A1 (0.43) | MAPTHSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL7982986 | 0.72 | FKBP1A (0.47) | ALDH1A1KMT2AMEN1CCNCCDK8 | |
| SCHEMBL7982982 | 0.72 | FKBP1A (0.47) | ALDH1A1KMT2AMEN1CCNCCDK8 | |
| SCHEMBL7966272 | 0.71 | PTAFR (0.45) | PTAFRHPGDHTTPOLB | |
| SCHEMBL7979963 | 0.71 | PTAFR (0.47) | PTAFRHPGDHTTEPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |