Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982543 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTFNTAFNTB | |
| SCHEMBL8022664 | 0.92 | C3AR1 (0.45) | C3AR1 | |
| SCHEMBL7979904 | 0.85 | NAPRT (0.48) | SMN1; SMN2POLBHPGD | |
| SCHEMBL7979905 | 0.85 | NAPRT (0.48) | SMN1; SMN2POLBHPGD | |
| SCHEMBL7976781 | 0.85 | ECE1 (0.48) | ALDH1A1MAPTSMN1; SMN2POLBHPGD | |
| SCHEMBL7976785 | 0.85 | ECE1 (0.48) | ALDH1A1MAPTSMN1; SMN2POLBHPGD | |
| Oxalic Acid SCHEMBL7978632 | 0.83 | MAPT (0.43) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7978380 | 0.83 | LMNA (0.46) | ALDH1A1MAPTSMN1; SMN2POLBHPGD | |
| SCHEMBL7978383 | 0.83 | LMNA (0.46) | ALDH1A1MAPTSMN1; SMN2POLBHPGD | |
| SCHEMBL7966499 | 0.81 | SIGMAR1 (0.44) | ALDH1A1MEN1KMT2AC3AR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | claimed |
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |