Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984282 | 0.81 | MAPK1 (0.53) | L3MBTL1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL4084676 | 0.77 | L3MBTL1 (0.56) | L3MBTL1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL16404343 | 0.72 | MAOA (0.50) | L3MBTL1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL92745 | 0.71 | KMT2A (0.50) | L3MBTL1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL28224409 | 0.70 | L3MBTL1 (0.49) | L3MBTL1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL854445 | 0.70 | TSHR (0.59) | L3MBTL1MAPTMEN1KMT2AHRH3 | |
| SCHEMBL2261435 | 0.70 | MAOA (0.52) | L3MBTL1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL1367959 | 0.70 | KDM4E (0.52) | MAPTLMNAKMT2ATDP1NPSR1 | |
| SCHEMBL859288 | 0.70 | ALDH1A1 (0.54) | L3MBTL1MAPTLMNAMEN1KMT2A | |
| SCHEMBL7978349 | 0.69 | KMT2A (0.74) | MAPTLMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |