SCHEMBL854445

SCHEMBL854445

N#Cc1ccc(Cc2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.59
▸ MAOB P27338 5/20 0.59
▸ CALM1 P0DP23 1/20 0.57
▸ MAOA P21397 4/20 0.57
▸ LOXL2 Q9Y4K0 2/20 0.56
▸ CYP2A6 P11509 1/20 0.54
▸ SAE1 Q9UBE0 1/20 0.53
▸ UBA2 Q9UBT2 1/20 0.53
▸ MAPT P10636 1/20 0.53
▸ NPC1 O15118 3/20 0.47
▸ RAB9A P51151 2/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ GAA P10253 1/20 0.47
▸ CRHBP P24387 1/20 0.47
▸ CRHR2 Q13324 1/20 0.47
▸ HRH3 Q9Y5N1 1/20 0.47
▸ LTA4H P09960 1/20 0.45
▸ KDM1A O60341 1/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ MEN1 O00255 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1344068 0.90 LOXL2 (0.65) TSHRMAOBMAOALOXL2CYP2A6
SCHEMBL20240289 0.88 MAOB (0.62) TSHRMAOBMAOALOXL2SMN1; SMN2
SCHEMBL6960019 0.86 MAOB (0.66) TSHRMAOBMAOALOXL2CYP2A6
SCHEMBL21386336 0.85 MAOB (0.46) TSHRMAOBMAOALOXL2SAE1
SCHEMBL7311874 0.85 MAOB (0.86) MAOBMAOAMAPTRAB9ASMN1; SMN2
SCHEMBL31739226 0.85 MAOB (0.46) TSHRMAOBMAOALOXL2SAE1
SCHEMBL14155434 0.83 LOXL2 (0.58) TSHRLOXL2CYP2A6SAE1UBA2
SCHEMBL16848648 0.83 LOXL2 (0.58) TSHRLOXL2CYP2A6SAE1UBA2
SCHEMBL19655694 0.82 CALM1 (0.52) TSHRMAOBCALM1MAOAHRH3
SCHEMBL6957742 0.82 MAOB (0.61) TSHRMAOBMAOALOXL2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367649-A1 PHOTOCATALYSTS, PREPARATION AND USE THEREOF THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) 2025-12-04 — — US disclosed
US-20230247899-A1 ORGANIC ELECTRONIC ELEMENT CONTAINING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE THEREFOR DUK SAN NEOLUX CO., LTD. (KR) 2023-08-03 — — US disclosed
US-20230240141-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2023-07-27 — — US disclosed
WO-2023077218-A1 PHOTOCATALYSTS, PREPARATION AND USE THEREOF THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY (CA) 2023-05-11 — — WO disclosed
CN-112851608-B Catalytic oxidation synthesis method of 2-diaryl methyl benzofuran compound 浙江工业大学 2022-07-15 — — CN disclosed
EP-3538617-B1 SOLDER MASK INKJET INKS FOR MANUFACTURING PRINTED CIRCUIT BOARDS AGFA GEVAERT NV (BE) 2021-09-29 — — EP disclosed
WO-2021136034-A1 ORGANIC COMPOUND, USE THEREOF AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 陕西莱特光电材料股份有限公司 2021-07-08 — — WO disclosed
CN-112851608-A Catalytic oxidation synthesis method of 2-diaryl methyl benzofuran compound 浙江工业大学 2021-05-28 — — CN disclosed
CN-112300011-A Aryl amine derivative containing bifluorene and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2021-02-02 — — CN disclosed
EP-3345894-A1 COMPOUND HAVING PROTEIN TYROSINE PHOSPHATASE SHP-1 AGONIST ACTIVITY Chen, Kuenfeng (TW) 2018-07-11 — — EP disclosed
WO-2002057264-A1 PYRROLE DERIVATES FOR TREATING CYTOKINE MEDIATED DISEASES SANKYO COMPANY LIMITED (JP) 2002-07-25 — — WO disclosed
US-6277998-B1 REACTING 2-CYANO-4-OXO-4H-BENZOPYRAN COMPOUND WITH HYDROGEN SULFIDE AND THEN REACTING PROUDCT WITH ALKYL HALIDE; REACTING THE PRODUCT WITH HYDRAZINE OR ITS SALT AND THEN WITH NITROUS ACID COMPOUND TO OBTAIN TETRAZOLE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-21 — — US disclosed
US-6191289-B1 REACTING A 4-OXO-4H-BENZOPYRAN GROUP SUBSTITUTED WITH AMIDE OR A PHENYL GROUP IN ITS 2 POSITION IS REACTED WITH ANHYDROUS HYDRAZINE OR SALT IN PRESENCE OF CATALYST FOLLOWED BY REACTING WITH NITROUS ACID OR SALT TO FORM TETRAZOLE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-02-20 — — US disclosed
EP-1070711-A2 Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses Sankyo Company Limited (JP) 2001-01-24 — — EP disclosed
CN-1241185-A Novel heterocyclic substituted pyrrolidine amide derivatives HOECHST MARION ROUSSEL INC (US) 2000-01-12 — — CN disclosed
US-5874593-A SULFUR CONTAINING AMIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-23 — — US disclosed
US-5792840-A SUBSTITUTED GLUCOPYRANOSYL PHOSPHATES SANKYO COMPANY, LIMITED (JP) 1998-08-11 — — US disclosed
EP-0711762-A1 PROCESS FOR PRODUCING TETRAZOLE COMPOUND AND INTERMEDIATE THEREFOR SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-05-15 — — EP disclosed
EP-0437016-B1 Lipid A analogues having immunoactivating and anti-tumour activity SANKYO CO (JP) 1996-05-01 — — EP disclosed
EP-0437016-A2 Lipid A analogues having immunoactivating and anti-tumour activity Sankyo Company Limited (JP) 1991-07-17 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230247899-A1 ORGANIC ELECTRONIC ELEMENT CONTAINING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE THEREFOR SLC39A11, LEF1, SLC39A14 TSHR 4383/4885MAOB 1244/4885CALM1 1610/4885
US-20230240141-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE THEREOF ESR1, GPX1, LEF1 TSHR 4596/4885MAOB 725/4885CALM1 1543/4885
US-20250367649-A1 PHOTOCATALYSTS, PREPARATION AND USE THEREOF PPOX, AOX1, CYP3A7 TSHR 4214/4885MAOB 138/4885CALM1 4598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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