Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 8/20 | 0.68 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.56 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7225842 | 0.81 | GABRA5 (1.00) | GABRA5GABRA1 | |
| SCHEMBL4036357 | 0.78 | GABRA5 (0.80) | GABRA5GABRA1 | |
| SCHEMBL7979757 | 0.75 | MAPT (0.50) | PIK3R1PIK3CA | |
| SCHEMBL7969979 | 0.75 | MAPT (0.50) | PIK3R1PIK3CA | |
| SCHEMBL17421084 | 0.74 | GABRA5 (0.69) | GABRA5GABRA1 | |
| SCHEMBL2865248 | 0.71 | HTT (0.52) | PIK3R1PIK3CA | |
| SCHEMBL13025167 | 0.71 | SRC (0.44) | PIK3R1PIK3CA | |
| SCHEMBL7032527 | 0.70 | QPCT (0.53) | — | |
| SCHEMBL20401101 | 0.70 | GLS (0.57) | — | |
| SCHEMBL2862612 | 0.70 | IDO1 (0.56) | PIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |