Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 11/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7986635 | 0.99 | NPC1 (0.39) | NPC1RAB9AKMT2ACCR5SCD5 | |
| SCHEMBL7982022 | 0.85 | DRD2 (0.36) | CCR5OPRL1KCNH2 | |
| Hydrochloric Acid SCHEMBL7983158 | 0.84 | DRD2 (0.36) | CCR5OPRL1KCNH2 | |
| SCHEMBL7983161 | 0.78 | ALDH1A1 (0.43) | KMT2AKCNH2 | |
| SCHEMBL7986651 | 0.78 | USP5 (0.38) | — | |
| SCHEMBL7982970 | 0.78 | ADRA1D (0.45) | — | |
| Hydrochloric Acid SCHEMBL7972919 | 0.77 | ADRA1D (0.44) | — | |
| Hydrochloric Acid SCHEMBL7971588 | 0.77 | USP5 (0.38) | — | |
| Hydrochloric Acid SCHEMBL7986162 | 0.77 | ALDH1A1 (0.43) | KMT2AKCNH2 | |
| SCHEMBL7984507 | 0.77 | OGA (0.40) | KMT2ACHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |