Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18172845 | 0.81 | TSHR (0.40) | MEN1KMT2AALDH1A1TSHRTP53 | |
| SCHEMBL28986134 | 0.81 | TRPM8 (0.47) | SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL30264826 | 0.80 | HSP90AA1 (0.47) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL572741 | 0.80 | ALDH1A1 (0.59) | SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL19716900 | 0.79 | TSHR (0.41) | MEN1KMT2AALDH1A1TSHRTP53 | |
| SCHEMBL7439248 | 0.79 | MEN1 (0.46) | SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL219603 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL27627978 | 0.78 | MEN1 (0.49) | SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL25960256 | 0.78 | MEN1 (0.49) | SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL4514025 | 0.78 | MEN1 (0.49) | SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674040-B2 | Pyridyldiamido transition metal complexes, production and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-03-18 | — | — | US | disclosed |
| US-8394902-B2 | Pyridyldiamido transition metal complexes, production and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-03-12 | — | — | US | disclosed |
| US-20120071616-A1 | Pyridyldiamido Transition Metal Complexes, Production And Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-03-22 | — | — | US | disclosed |
| US-20110224391-A1 | Pyridyldiamido Transition Metal Complexes, Production and Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224391-A1 | Pyridyldiamido Transition Metal Complexes, Production and Use Thereof | PICALM, PARN, PCBP1 | SMN1; SMN2 2402/4885MEN1 2585/4885KMT2A 3696/4885 |
| US-20120071616-A1 | Pyridyldiamido Transition Metal Complexes, Production And Use Thereof | PNPO, PLPBP, PDXK | SMN1; SMN2 2977/4885MEN1 3180/4885KMT2A 3516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.