Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | MPO | P05164 | 5/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.33 |
| ▸ | HTR1B | P28222 | 2/20 | 0.33 |
| ▸ | HTR5A | P47898 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR1E | P28566 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994177 | 0.80 | GPR84 (0.48) | GPR84HTR2AHTR1AHTR2CHTR7 | |
| SCHEMBL8001659 | 0.80 | MPO (0.62) | HTR2AHTR1AMPOSLC6A4HTR2C | |
| SCHEMBL7998078 | 0.80 | GPR84 (0.48) | GPR84HTR2ASLC6A4HTR2CTDP1 | |
| SCHEMBL7997361 | 0.80 | HTR2A (0.41) | HTR2AHTR2CTDP1NPSR1MEN1 | |
| SCHEMBL7993961 | 0.78 | HTR2A (0.53) | GPR84HTR2AHTR1AMPOSLC6A4 | |
| SCHEMBL7997830 | 0.75 | HTR2A (0.53) | GPR84HTR2AHTR1AMPOSLC6A4 | |
| SCHEMBL7984083 | 0.74 | HTR2B (0.52) | HTR2AHTR1AMPOSLC6A4HTR2C | |
| SCHEMBL7997354 | 0.73 | GPR84 (0.48) | GPR84HTR2AHTR1AMPOSLC6A4 | |
| SCHEMBL25423399 | 0.73 | GPR84 (0.71) | GPR84HTR2AHTR1AMPOHTR2C | |
| SCHEMBL31730855 | 0.73 | GPR84 (0.71) | GPR84HTR2AHTR1AMPOHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040183-A1 | 1-AMINOALKYL-1H-INDOLES FOR TREATING GLAUCOMA | ALCON UNIVERSAL LTD. (CH) | 2001-06-07 | — | — | WO | disclosed |