Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994177 | 0.86 | GPR84 (0.48) | GPR84HTR2AHTR2CGAANPSR1 | |
| SCHEMBL7997361 | 0.86 | HTR2A (0.41) | HTR2AHTR2CGAANPSR1MTNR1A | |
| SCHEMBL7983657 | 0.80 | GPR84 (0.49) | GPR84SLC6A4HTR2AHTR2CNPSR1 | |
| SCHEMBL7983652 | 0.79 | SLC6A4 (0.41) | GPR84SLC6A4HTR2AHTR2CNPSR1 | |
| SCHEMBL7993961 | 0.77 | HTR2A (0.53) | GPR84SLC6A4HTR2AHTR2CMTNR1A | |
| Oxalic Acid SCHEMBL2533945 | 0.72 | HTR2C (0.60) | GPR84SLC6A4NR4A2HTR2AHTR2C | |
| SCHEMBL8001659 | 0.72 | MPO (0.62) | SLC6A4HTR2AHTR2CMTNR1AMTNR1B | |
| SCHEMBL7997830 | 0.72 | HTR2A (0.53) | GPR84SLC6A4NR4A2HTR2AHTR2C | |
| SCHEMBL7994191 | 0.72 | LMNA (0.44) | HTR2AGAANPSR1MTNR1AMTNR1B | |
| SCHEMBL16540351 | 0.72 | GPR17 (0.69) | GPR84SLC6A4NR4A2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040183-A1 | 1-AMINOALKYL-1H-INDOLES FOR TREATING GLAUCOMA | ALCON UNIVERSAL LTD. (CH) | 2001-06-07 | — | — | WO | disclosed |