Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR1E | P28566 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998078 | 0.86 | GPR84 (0.48) | GPR84HTR2AMTNR1AMTNR1BHTR2C | |
| SCHEMBL7997361 | 0.86 | HTR2A (0.41) | HTR2AMTNR1AMTNR1BHTR2CGAA | |
| SCHEMBL7983657 | 0.80 | GPR84 (0.49) | GPR84HTR2AHTR2CNPSR1HTR1A | |
| SCHEMBL18837119 | 0.76 | GPR84 (0.63) | GPR84HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL1462665 | 0.75 | GPR84 (0.55) | GPR84HTR2AMTNR1AMTNR1BHTR2C | |
| SCHEMBL7994191 | 0.74 | LMNA (0.44) | HTR2AMTNR1AMTNR1BGAANPSR1 | |
| SCHEMBL25772433 | 0.73 | GPR84 (0.59) | GPR84HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL7997990 | 0.73 | HTR2A (0.57) | HTR2AMTNR1AMTNR1BHTR2CGAA | |
| SCHEMBL7995675 | 0.73 | HTR2A (0.57) | HTR2AMTNR1AMTNR1BHTR2CGAA | |
| SCHEMBL8001578 | 0.73 | HTR2A (0.57) | HTR2AMTNR1AMTNR1BHTR2CGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040183-A1 | 1-AMINOALKYL-1H-INDOLES FOR TREATING GLAUCOMA | ALCON UNIVERSAL LTD. (CH) | 2001-06-07 | — | — | WO | disclosed |