Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987960 | 0.90 | CYP11B1 (0.32) | CYP11B1CYP11B2TLR7HPGD | |
| SCHEMBL7974260 | 0.89 | CYP11B1 (0.47) | CYP11B1CYP11B2ALDH1A1HPGDGAA | |
| SCHEMBL7987434 | 0.88 | CYP11B1 (0.42) | CYP11B1CYP11B2ALDH1A1TLR7HPGD | |
| SCHEMBL7988129 | 0.84 | MET (0.44) | ALDH1A1TLR7HPGDMETGAA | |
| SCHEMBL7975252 | 0.84 | HPGD (0.45) | CYP11B1CYP11B2ALDH1A1HPGDGAA | |
| SCHEMBL7985521 | 0.84 | ALDH1A1 (0.41) | ALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL7985245 | 0.83 | HSP90AA1 (0.44) | ALDH1A1TLR7 | |
| SCHEMBL7984526 | 0.82 | MET (0.46) | CYP11B1CYP11B2ALDH1A1HPGDMET | |
| SCHEMBL7974271 | 0.81 | TNF (0.46) | ALDH1A1TLR7GAASMN1; SMN2 | |
| SCHEMBL7984754 | 0.80 | SMN1; SMN2 (0.47) | CYP11B1CYP11B2GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |