Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | DBH | P09172 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987434 | 0.91 | CYP11B1 (0.42) | METHPGDALDH1A1SMN1; SMN2TLR7 | |
| SCHEMBL7984526 | 0.90 | MET (0.46) | METHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7975252 | 0.89 | HPGD (0.45) | HPGDALDH1A1SMN1; SMN2GAAPOLB | |
| SCHEMBL7984468 | 0.87 | ABCC8 (0.46) | METHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7973934 | 0.87 | CYP11B1 (0.45) | METHPGDALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8059823 | 0.87 | MEN1 (0.45) | HPGDALDH1A1SMN1; SMN2GAAPOLB | |
| SCHEMBL7987782 | 0.85 | NPC1 (0.44) | HPGDALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL7984378 | 0.84 | CYP11B1 (0.42) | METHPGDALDH1A1SMN1; SMN2TLR7 | |
| SCHEMBL7985651 | 0.84 | CYP1A2 (0.41) | METHPGDALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7984754 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |