Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987469 | 0.87 | TLR7 (0.44) | TLR7MEN1KMT2ATLR8 | |
| SCHEMBL7984378 | 0.83 | CYP11B1 (0.42) | TLR7ALDH1A1 | |
| SCHEMBL7984512 | 0.80 | GAA (0.50) | MEN1KMT2A | |
| SCHEMBL7975252 | 0.78 | HPGD (0.45) | MEN1ALDH1A1KMT2APOLB | |
| SCHEMBL7988129 | 0.78 | MET (0.44) | TLR7ALDH1A1KMT2APOLB | |
| SCHEMBL7987443 | 0.76 | GAA (0.37) | TLR7MEN1ALDH1A1KMT2A | |
| SCHEMBL7984526 | 0.76 | MET (0.46) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL7985651 | 0.75 | CYP1A2 (0.41) | ALDH1A1KMT2A | |
| SCHEMBL7985241 | 0.75 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1TLR7PTGS2KDM4E | |
| SCHEMBL7984754 | 0.74 | SMN1; SMN2 (0.47) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |