Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991557 | 0.90 | LMNA (0.43) | SMN1; SMN2LMNACYP11B1CYP11B2HTT | |
| SCHEMBL7985565 | 0.90 | HDAC6 (0.40) | SMN1; SMN2LMNACYP11B1CYP11B2HTT | |
| SCHEMBL7984659 | 0.90 | ALDH1A1 (0.44) | SMN1; SMN2LMNACYP11B1CYP11B2HPGD | |
| SCHEMBL7991597 | 0.89 | PDE4B (0.39) | SMN1; SMN2LMNACYP11B1CYP11B2HTT | |
| SCHEMBL7974416 | 0.89 | MET (0.43) | LMNACYP11B1CYP11B2HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL7987662 | 0.89 | ALDH1A1 (0.43) | SMN1; SMN2LMNACYP11B1CYP11B2HPGD | |
| SCHEMBL7991400 | 0.89 | NR1H4 (0.43) | LMNACSNK1DHPGDKDM4EALDH1A1 | |
| SCHEMBL7974469 | 0.88 | HDAC1 (0.40) | SMN1; SMN2LMNACYP11B1CYP11B2HTT | |
| SCHEMBL7984717 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNACYP11B1CYP11B2HTT | |
| SCHEMBL7985060 | 0.86 | ADORA2A (0.39) | SMN1; SMN2LMNACYP11B1CYP11B2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |