Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 6/20 | 0.61 |
| ▸ | FLT4 | P35916 | 6/20 | 0.61 |
| ▸ | KDR | P35968 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | BCL2 | P10415 | 1/20 | 0.52 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16320154 | 0.91 | MMP1 (0.57) | FLT1FLT4KDRALDH1A1KDM4E | |
| SCHEMBL7973491 | 0.88 | FLT1 (0.56) | FLT1FLT4KDRALDH1A1KDM4E | |
| SCHEMBL7990728 | 0.83 | HDAC1 (0.59) | ALDH1A1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL24052290 | 0.83 | HDAC8 (0.59) | LMNAHTTSMN1; SMN2HDAC2 | |
| SCHEMBL7987132 | 0.81 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1LMNAPOLBGAA | |
| SCHEMBL7990884 | 0.81 | OGG1 (0.55) | ALDH1A1KDM4EL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL24052028 | 0.81 | PARP10 (0.46) | FLT1FLT4KDRALDH1A1KDM4E | |
| SCHEMBL24420690 | 0.81 | LMNA (0.51) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL7987067 | 0.81 | PLK1 (0.61) | ALDH1A1LMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL1370670 | 0.81 | LMNA (0.54) | FLT1FLT4KDRALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |