Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973227 | 0.88 | HDAC3 (0.53) | OGG1HDAC3HDAC1HDAC2POLB | |
| SCHEMBL24052290 | 0.83 | HDAC8 (0.59) | HDAC2HDAC8HDAC6HPGDSMN1; SMN2 | |
| SCHEMBL7990728 | 0.83 | HDAC1 (0.59) | HDAC1POLBHDAC6PTGS2ALDH1A1 | |
| SCHEMBL7987132 | 0.81 | ALDH1A1 (0.50) | HDAC3HDAC1HDAC2POLBPTGS2 | |
| SCHEMBL24420690 | 0.81 | LMNA (0.51) | HDAC3HDAC1HDAC2POLBHDAC10 | |
| SCHEMBL7987067 | 0.81 | PLK1 (0.61) | POLBHDAC8HDAC6ALDH1A1MAPT | |
| SCHEMBL24052028 | 0.81 | PARP10 (0.46) | HDAC8HDAC6ALDH1A1NPC1HPGD | |
| SCHEMBL7984827 | 0.81 | FLT1 (0.61) | HDAC3HDAC1HDAC2POLBCTDSP1 | |
| SCHEMBL1370670 | 0.81 | LMNA (0.54) | HDAC3HDAC1HDAC2POLBHDAC8 | |
| SCHEMBL7118965 | 0.81 | ALDH1A1 (0.58) | OGG1HDAC3HDAC1HDAC2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |