Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 2/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974646 | 0.90 | MAPK14 (0.47) | MAPK14SMN1; SMN2METMAPK1GAA | |
| SCHEMBL7988454 | 0.89 | MAPK14 (0.41) | MAPK14UBE2NMETGAA | |
| SCHEMBL7974309 | 0.88 | CYP11B1 (0.45) | MAPK14SMN1; SMN2HTTMETGAA | |
| SCHEMBL7988184 | 0.86 | MET (0.42) | MAPK14SMN1; SMN2HTTL3MBTL1MET | |
| SCHEMBL7985870 | 0.85 | GAA (0.50) | MAPK14YTHDC1L3MBTL1MAPK1GAA | |
| SCHEMBL7988668 | 0.85 | SMN1; SMN2 (0.44) | YTHDC1SMN1; SMN2GLAHTTUBE2N | |
| SCHEMBL7988817 | 0.84 | SMN1; SMN2 (0.43) | MAPK14YTHDC1SMN1; SMN2GLAHTT | |
| SCHEMBL7992177 | 0.84 | SMN1; SMN2 (0.42) | YTHDC1SMN1; SMN2GLAHTTUBE2N | |
| SCHEMBL7974060 | 0.84 | SMN1; SMN2 (0.41) | MAPK14SMN1; SMN2HTTL3MBTL1MET | |
| SCHEMBL7973626 | 0.84 | SMN1; SMN2 (0.45) | YTHDC1SMN1; SMN2GLAHTTUBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |