Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20164006 | 0.71 | ALDH1A1 (0.43) | EPHX1EPHX2ALDH1A1LMNAKDM4E | |
| SCHEMBL20164004 | 0.71 | ALDH1A1 (0.43) | EPHX1EPHX2ALDH1A1LMNAKDM4E | |
| SCHEMBL16933816 | 0.69 | HCRTR1 (0.43) | LMNAHPGD | |
| SCHEMBL16933820 | 0.69 | HCRTR1 (0.43) | LMNAHPGD | |
| SCHEMBL7561613 | 0.69 | EPHX1 (0.45) | EPHX1EPHX2FKBP1ATBXAS1 | |
| SCHEMBL17007540 | 0.67 | LMNA (0.40) | ALDH1A1LMNAHTTKMT2ARAB9A | |
| SCHEMBL15913826 | 0.67 | HCRTR1 (0.34) | — | |
| SCHEMBL7984933 | 0.66 | MAPT (0.46) | ALDH1A1LMNAMAPTFKBP1AMEN1 | |
| SCHEMBL15913246 | 0.66 | HCRTR1 (0.33) | — | |
| SCHEMBL7995095 | 0.64 | FKBP1A (0.57) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284779-B1 | NERVOUS SYSTEM DISORDERS | SCHERING AKTIIENGESELLSCHAFT (DE) | 2001-09-04 | — | — | US | disclosed |
| WO-2000046222-A1 | HETEROAROMATIC COMPOUNDS WITH NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-08-10 | — | — | WO | disclosed |