Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | STAT6 | P42226 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974074 | 0.94 | CXCR2 (0.45) | CXCR2PARNCNOT7GRIN1GRIN2B | |
| SCHEMBL7988017 | 0.90 | KDM4E (0.43) | CXCR2KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL7987953 | 0.89 | PDE2A (0.46) | CXCR2MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7987255 | 0.86 | PARN (0.48) | ALDH1A1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL7975271 | 0.86 | CNOT7 (0.56) | CXCR2ALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL7984663 | 0.85 | CNOT7 (0.49) | KDM4EMEN1NPC1ALDH1A1HPGD | |
| SCHEMBL7974015 | 0.85 | PARN (0.49) | CXCR2ALDH1A1CYP1A2CYP2C9HTT | |
| SCHEMBL7985342 | 0.84 | CNOT7 (0.51) | CXCR2ALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL7988597 | 0.84 | PARN (0.48) | NPC1ALDH1A1PKMHPGDRAB9A | |
| Hydrochloric Acid SCHEMBL7987663 | 0.84 | CNOT7 (0.48) | KDM4EMEN1NPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |