Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 6/20 | 0.46 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.46 |
| ▸ | PARN | O95453 | 1/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974492 | 0.89 | ABCC8 (0.47) | PDE2ACNOT7PARNTNKSTNKS2 | |
| SCHEMBL7975271 | 0.89 | CNOT7 (0.56) | CNOT7PARNCXCR2ADORA3KMT2A | |
| SCHEMBL7984975 | 0.89 | CXCR2 (0.53) | CNOT7PARNCXCR2SCN2AMEN1 | |
| SCHEMBL7974074 | 0.89 | CXCR2 (0.45) | CNOT7PARNCXCR2ADORA3SCN2A | |
| SCHEMBL7986522 | 0.88 | CNOT7 (0.48) | CNOT7PARNTNKSTNKS2MEN1 | |
| SCHEMBL7991406 | 0.86 | CNOT7 (0.49) | CNOT7PARNCXCR2TNKSTNKS2 | |
| SCHEMBL7984720 | 0.85 | CNOT7 (0.48) | CNOT7PARNADORA3TNKSTNKS2 | |
| SCHEMBL7988017 | 0.85 | KDM4E (0.43) | CXCR2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7974444 | 0.84 | CNOT7 (0.52) | CNOT7PARNCXCR2KMT2AALDH1A1 | |
| SCHEMBL7974508 | 0.83 | CNOT7 (0.51) | CNOT7PARNTNKSTNKS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |