Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984482 | 0.94 | GBA1 (0.42) | GBA1SMN1; SMN2LMNAALOX15TSHR | |
| SCHEMBL7984465 | 0.86 | CNOT7 (0.41) | LMNATSHRMAPK14MAPTCNOT7 | |
| SCHEMBL7974276 | 0.83 | HTT (0.39) | MAPK14MAPTHTTCNOT7ALDH1A1 | |
| SCHEMBL7974646 | 0.81 | MAPK14 (0.47) | SMN1; SMN2TSHRMAPK14MAPTCNOT7 | |
| SCHEMBL7973917 | 0.78 | LMNA (0.40) | LMNAMAPK14MAPTTP53ALDH1A1 | |
| SCHEMBL7985536 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAALOX15TSHRMAPK14 | |
| SCHEMBL7985444 | 0.77 | CNOT7 (0.41) | SMN1; SMN2LMNAALOX15TSHRMAPK14 | |
| SCHEMBL7988184 | 0.76 | MET (0.42) | SMN1; SMN2LMNATSHRMAPK14MAPT | |
| SCHEMBL7985870 | 0.76 | GAA (0.50) | TSHRMAPK14TP53L3MBTL1ALDH1A1 | |
| SCHEMBL7974060 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAMAPK14RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |