Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984728 | 0.91 | NR1H4 (0.41) | PAX8ALDH1A1NR1H4 | |
| SCHEMBL7974156 | 0.90 | BRD4 (0.43) | PAX8HPGDMCL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7988794 | 0.83 | NR1H4 (0.40) | PAX8MCL1NR1H4 | |
| SCHEMBL7984487 | 0.83 | ADORA3 (0.43) | HPGDSMN1; SMN2ALDH1A1SLC2A1ADORA3 | |
| SCHEMBL7985473 | 0.82 | HPGD (0.49) | PAX8HPGDMCL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7985457 | 0.80 | HTR2C (0.46) | HPGDMCL1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL7975267 | 0.79 | SMN1; SMN2 (0.46) | HPGDSMN1; SMN2ALDH1A1GAAADORA3 | |
| SCHEMBL7974025 | 0.78 | HTR2C (0.39) | HPGDMCL1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL7988917 | 0.78 | HTR2C (0.40) | HPGDMCL1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL7988558 | 0.78 | SMN1; SMN2 (0.43) | HPGDSMN1; SMN2ALDH1A1GAAADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |