Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 5/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | PDE1A | P54750 | 1/20 | 0.44 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988610 | 0.84 | GUSB (0.54) | ALDH1A1SMN1; SMN2HPGDKMT2AGAA | |
| SCHEMBL7974850 | 0.84 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2HPGDKMT2AGAA | |
| SCHEMBL7985535 | 0.83 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2HPGDKMT2AGAA | |
| SCHEMBL7974644 | 0.83 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2HPGDKMT2AGAA | |
| SCHEMBL7975123 | 0.83 | CXCR2 (0.50) | GAACXCR2ACP1 | |
| SCHEMBL7985230 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2HPGDKMT2AGAA | |
| SCHEMBL7985355 | 0.82 | GAA (0.56) | ALDH1A1SMN1; SMN2HPGDKMT2AGAA | |
| SCHEMBL7975265 | 0.81 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2HPGDKMT2AGAA | |
| SCHEMBL7985702 | 0.80 | HPGD (0.50) | ALDH1A1SMN1; SMN2HPGDKMT2AGAA | |
| SCHEMBL7974583 | 0.80 | GAA (0.59) | ALDH1A1SMN1; SMN2HPGDKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |