Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.39 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.39 |
| ▸ | PARN | O95453 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991403 | 0.89 | ABCC8 (0.43) | ABCC8KCNJ11NR1H4CNOT7PARN | |
| SCHEMBL7985012 | 0.89 | ABCC8 (0.43) | ABCC8KCNJ11NR1H4CNOT7PARN | |
| SCHEMBL7985568 | 0.89 | CNOT7 (0.41) | CNOT7PARNHDAC6HDAC1HSD17B13 | |
| SCHEMBL7992270 | 0.89 | ABCC8 (0.43) | ABCC8KCNJ11NR1H4CNOT7PARN | |
| SCHEMBL7974492 | 0.88 | ABCC8 (0.47) | ABCC8KCNJ11NR1H4CNOT7PARN | |
| SCHEMBL7985342 | 0.88 | CNOT7 (0.51) | CNOT7PARN | |
| SCHEMBL7984474 | 0.88 | ABCC8 (0.42) | ABCC8KCNJ11NR1H4CNOT7PARN | |
| SCHEMBL7988017 | 0.88 | KDM4E (0.43) | ABCC8KCNJ11HDAC6HDAC1 | |
| SCHEMBL7985619 | 0.87 | CNOT7 (0.41) | CNOT7PARNHDAC6HDAC1HSD17B13 | |
| SCHEMBL7985602 | 0.87 | SERPINE1 (0.45) | ABCC8KCNJ11HDAC6HDAC1SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |