Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.46 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984492 | 0.95 | ADORA2A (0.53) | KDM4EALDH1A1ADORA2AYTHDC1ADORA3 | |
| SCHEMBL7975241 | 0.91 | GAA (0.50) | NTRK1ADORA2AYTHDC1NPC1RAB9A | |
| SCHEMBL7992620 | 0.89 | NPC1 (0.53) | KDM4EALDH1A1YTHDC1NPC1RAB9A | |
| SCHEMBL7974581 | 0.89 | LMNA (0.51) | ALDH1A1IDO1NPC1RAB9AADORA3 | |
| SCHEMBL7988029 | 0.89 | IDO1 (0.47) | IDO1NPC1RAB9AADORA3HSD17B13 | |
| SCHEMBL7988506 | 0.87 | NTRK1 (0.48) | KDM4EALDH1A1NTRK1P2RY14YTHDC1 | |
| SCHEMBL7985375 | 0.86 | KDM4E (0.47) | KDM4EALDH1A1YTHDC1RAB9AADORA3 | |
| SCHEMBL7985033 | 0.85 | NLRP3 (0.46) | KDM4EALDH1A1NTRK1YTHDC1NPC1 | |
| SCHEMBL7984200 | 0.85 | SMN1; SMN2 (0.53) | ALDH1A1NPC1RAB9AADORA3HSD17B13 | |
| SCHEMBL7985070 | 0.85 | P2RY14 (0.48) | KDM4EALDH1A1P2RY14ADORA3KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |