Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MARS1 | P56192 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974853 | 0.88 | DPP4 (0.48) | CXCR2DPP4SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7984459 | 0.83 | NR1H2 (0.43) | SMN1; SMN2ALDH1A1HPGDGAAKMT2A | |
| SCHEMBL7974012 | 0.83 | ALDH1A1 (0.41) | CXCR2SMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL7985538 | 0.82 | SMN1; SMN2 (0.43) | DPP4SMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL7988668 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL7991405 | 0.81 | CYP11B1 (0.45) | SMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL7985425 | 0.81 | ACP1 (0.42) | SMN1; SMN2KMT2ACRHBPCRHR2P2RX7 | |
| SCHEMBL7984878 | 0.81 | MAPK14 (0.42) | SMN1; SMN2GAAP2RX7 | |
| SCHEMBL7975267 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1HPGDGAAKMT2A | |
| SCHEMBL7974646 | 0.80 | MAPK14 (0.47) | CXCR2DPP4SMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |