Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974745 | 0.87 | MAPK14 (0.40) | MAOBMAPK14 | |
| SCHEMBL7986104 | 0.86 | KDM4E (0.39) | KDM4ELMNASMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL7989153 | 0.77 | ALDH1A1 (0.43) | LMNASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7985834 | 0.77 | MEN1 (0.43) | SMN1; SMN2MAPK14CYP11B1CYP11B2HTT | |
| SCHEMBL7986045 | 0.74 | MEN1 (0.40) | MAPK14HTT | |
| SCHEMBL28961976 | 0.73 | MAOB (0.89) | MAOBLMNASMN1; SMN2ARGHSR | |
| SCHEMBL403151 | 0.71 | MAOB (1.00) | MAOBLMNASMN1; SMN2ARGHSR | |
| SCHEMBL7988190 | 0.71 | PDE10A (0.45) | MAPK14CYP11B1CYP11B2CYP1A2CYP2C9 | |
| SCHEMBL5619630 | 0.70 | LMNA (0.49) | MAOBLMNASMN1; SMN2ARCYP1A2 | |
| SCHEMBL7986965 | 0.69 | MAPT (0.41) | LMNASMN1; SMN2ARMAPK14CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042243-A2 | PROTEIN KINASE INHIBITORS | ADVANCED MEDICINE, INC. (US) | 2001-06-14 | — | — | WO | disclosed |