Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991980 | 0.87 | MAOB (0.51) | MAPK14MAOB | |
| SCHEMBL7989153 | 0.80 | ALDH1A1 (0.43) | KMT2AMEN1MAPK1 | |
| SCHEMBL7985834 | 0.78 | MEN1 (0.43) | MAPK14KMT2AMEN1 | |
| SCHEMBL7986045 | 0.75 | MEN1 (0.40) | MAPK14KMT2AMEN1SYK | |
| SCHEMBL7988190 | 0.74 | PDE10A (0.45) | MAPK14KMT2AMEN1MAPK1 | |
| SCHEMBL7986965 | 0.72 | MAPT (0.41) | MAPK14KMT2AMEN1MAPK1 | |
| SCHEMBL7986104 | 0.72 | KDM4E (0.39) | MAPK14 | |
| SCHEMBL464352 | 0.71 | RXRA (0.66) | RXRARXRBKMT2AMEN1CHRNA7 | |
| SCHEMBL5619630 | 0.70 | LMNA (0.49) | KMT2AMEN1BCHEMAOB | |
| SCHEMBL11855314 | 0.69 | LTA4H (0.60) | RXRARXRBCHRNA7PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042243-A2 | PROTEIN KINASE INHIBITORS | ADVANCED MEDICINE, INC. (US) | 2001-06-14 | — | — | WO | disclosed |