Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988190 | 0.88 | PDE10A (0.45) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL7989153 | 0.86 | ALDH1A1 (0.43) | MAPTTSHRRAB9AMEN1KMT2A | |
| SCHEMBL7986045 | 0.86 | MEN1 (0.40) | MAPTMEN1KMT2APDE10AMAPK14 | |
| SCHEMBL7986104 | 0.80 | KDM4E (0.39) | MAPTLMNAMAPK14CYP1A2CYP2C9 | |
| SCHEMBL7985834 | 0.77 | MEN1 (0.43) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL7989104 | 0.75 | PPP1CA (0.50) | MAPTTSHRKMT2APDE10AMAPK1 | |
| SCHEMBL7985956 | 0.73 | MAPK14 (0.41) | MAPTMEN1KMT2APDE10AMAPK14 | |
| SCHEMBL7974674 | 0.73 | MEN1 (0.44) | MAPTTSHRRAB9ANPC1MEN1 | |
| SCHEMBL7992031 | 0.71 | MAPK14 (0.41) | MAPTMEN1KMT2AMAPK14HTT | |
| SCHEMBL4046168 | 0.71 | LTA4H (0.69) | MEN1KMT2ASMN1; SMN2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042243-A2 | PROTEIN KINASE INHIBITORS | ADVANCED MEDICINE, INC. (US) | 2001-06-14 | — | — | WO | disclosed |