Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | BAX | Q07812 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCND3 | P30281 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986965 | 0.86 | MAPT (0.41) | MEN1HTTKMT2AMAPK14MAPT | |
| SCHEMBL7985834 | 0.85 | MEN1 (0.43) | MEN1HTTKMT2AMAPK14PIK3CA | |
| SCHEMBL7988190 | 0.83 | PDE10A (0.45) | MEN1HTTKMT2AMAPK14PIK3CA | |
| SCHEMBL7989153 | 0.82 | ALDH1A1 (0.43) | MEN1HTTKMT2ALTA4HMAPT | |
| SCHEMBL7986104 | 0.76 | KDM4E (0.39) | MAPK14MAPTL3MBTL1 | |
| SCHEMBL7985956 | 0.76 | MAPK14 (0.41) | MEN1HTTKMT2AMAPK14MAPT | |
| SCHEMBL7974745 | 0.75 | MAPK14 (0.40) | MEN1KMT2AMAPK14SYK | |
| SCHEMBL7991980 | 0.74 | MAOB (0.51) | HTTMAPK14 | |
| SCHEMBL7992858 | 0.73 | MAPK14 (0.40) | MEN1HTTKMT2AMAPK14SYK | |
| SCHEMBL7989104 | 0.72 | PPP1CA (0.50) | KMT2AMAPK14MAPTL3MBTL1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042243-A2 | PROTEIN KINASE INHIBITORS | ADVANCED MEDICINE, INC. (US) | 2001-06-14 | — | — | WO | disclosed |