Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 8/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 17/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985989 | 0.83 | FFAR1 (0.39) | — | |
| SCHEMBL7989516 | 0.80 | MMP3 (0.42) | MMP3MMP9MMP8MMP2MMP1 | |
| SCHEMBL7987529 | 0.80 | MMP3 (0.42) | MMP3MMP9MMP8MMP2MMP1 | |
| SCHEMBL7975565 | 0.77 | FOLH1 (0.47) | — | |
| SCHEMBL7975562 | 0.77 | FOLH1 (0.47) | — | |
| SCHEMBL7977831 | 0.77 | MMP2 (0.44) | MMP3MMP9MMP8MMP2MMP1 | |
| SCHEMBL7977828 | 0.77 | MMP2 (0.44) | MMP3MMP9MMP8MMP2MMP1 | |
| SCHEMBL7986860 | 0.75 | MMP2 (0.38) | MMP3MMP2ITGB3 | |
| SCHEMBL7986858 | 0.75 | MMP2 (0.46) | MMP3MMP2MMP1 | |
| SCHEMBL7993697 | 0.75 | KMT2A (0.40) | MMP9MMP8MMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |