Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986396 | 0.86 | DRD4 (0.44) | DRD2SIGMAR1GAAMAPTDRD4 | |
| SCHEMBL27468194 | 0.84 | TNKS2 (0.46) | PTGS2MAPT | |
| SCHEMBL6200943 | 0.80 | OPRM1 (0.40) | — | |
| SCHEMBL7983801 | 0.80 | ALDH1A1 (0.42) | — | |
| SCHEMBL4910773 | 0.78 | WEE1 (0.38) | GAAMAPT | |
| SCHEMBL29614674 | 0.76 | PARP1 (0.43) | MAPT | |
| SCHEMBL6644399 | 0.75 | HTR7 (0.37) | DHFRDRD2DRD3HTR1A | |
| SCHEMBL7986154 | 0.70 | HTR1A (0.53) | DRD2SIGMAR1DRD4DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL31491097 | 0.69 | PRKACA (0.40) | SIGMAR1 | |
| SCHEMBL7983420 | 0.69 | HTR1A (0.55) | DRD2SIGMAR1DRD4DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |