Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986506 | 1.00 | KDM4E (0.56) | KDM4EALDH1A1TDP1HTR1AACHE | |
| SCHEMBL3962101 | 0.84 | KDM4E (0.60) | KDM4EALDH1A1TDP1HTR1A | |
| SCHEMBL7985675 | 0.81 | SIGMAR1 (0.58) | KDM4EALDH1A1TDP1 | |
| SCHEMBL7985669 | 0.81 | SIGMAR1 (0.58) | KDM4EALDH1A1TDP1 | |
| SCHEMBL7986141 | 0.78 | SIGMAR1 (0.50) | ACHE | |
| SCHEMBL7986145 | 0.78 | SIGMAR1 (0.50) | ACHE | |
| SCHEMBL7986385 | 0.78 | ADRA1D (0.70) | — | |
| SCHEMBL7983385 | 0.78 | SIGMAR1 (0.55) | KDM4EALDH1A1TDP1HTR1AACHE | |
| SCHEMBL7983388 | 0.78 | SIGMAR1 (0.55) | KDM4EALDH1A1TDP1HTR1AACHE | |
| SCHEMBL3961898 | 0.77 | ALDH1A1 (0.59) | KDM4EALDH1A1TDP1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |