Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.38 |
| ▸ | FCER2 | P06734 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 9/20 | 0.37 |
| ▸ | MMP3 | P08254 | 4/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988005 | 0.87 | TACR1 (0.40) | MMP1FCER2TACR1PTGER1PTGER4 | |
| SCHEMBL7986859 | 0.82 | MMP9 (0.45) | MMP1MMP2MMP3 | |
| SCHEMBL7986858 | 0.80 | MMP2 (0.46) | MMP1MMP2MMP3 | |
| SCHEMBL7990393 | 0.77 | PTGER4 (0.39) | PTGER1PTGER4PTGER3 | |
| SCHEMBL7986628 | 0.77 | MMP2 (0.42) | MMP1MMP2MMP3 | |
| SCHEMBL7993694 | 0.77 | MMP2 (0.54) | MMP1MMP2TACR1 | |
| SCHEMBL7987314 | 0.75 | MME (0.41) | MMP1MMP2MMP3 | |
| SCHEMBL7990047 | 0.75 | PDF (0.50) | MMP1MMP2MMP3 | |
| SCHEMBL7977831 | 0.74 | MMP2 (0.44) | MMP1MMP2MMP3 | |
| SCHEMBL7977828 | 0.74 | MMP2 (0.44) | MMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |