Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 4/20 | 0.44 |
| ▸ | CCNH | P51946 | 4/20 | 0.44 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.44 |
| ▸ | CDK9 | P50750 | 3/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987194 | 0.92 | HTR6 (0.37) | CDK7CCNHMNAT1CCNT1CDK9 | |
| SCHEMBL7976272 | 0.91 | CCNT1 (0.41) | CDK7CCNHMNAT1CCNT1CDK9 | |
| SCHEMBL7513288 | 0.91 | CDK7 (0.47) | CDK7CCNHMNAT1CCNT1CDK9 | |
| SCHEMBL7990448 | 0.90 | CYP11B1 (0.40) | CDK7CCNHMNAT1CCNT1CDK9 | |
| SCHEMBL7976151 | 0.89 | CCNT1 (0.37) | CDK7CCNHMNAT1CCNT1CDK9 | |
| SCHEMBL7990894 | 0.89 | EGFR (0.42) | CDK7CCNHMNAT1CCNT1CDK9 | |
| SCHEMBL7991016 | 0.89 | CCNT1 (0.37) | CDK7CCNHMNAT1CCNT1CDK9 | |
| SCHEMBL7990500 | 0.87 | KDM1A (0.41) | CCNT1CDK9TGFBR1CHRNB4CHRNA3 | |
| SCHEMBL7990169 | 0.87 | PDE4B (0.37) | CDK7CCNHMNAT1CCNT1CDK9 | |
| SCHEMBL7976189 | 0.86 | CCNT1 (0.40) | CDK7CCNHMNAT1CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265403-B1 | TYROSINE INHIBITORS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |