Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4379847 | 0.80 | HTR2A (0.42) | MAOBHTR2AKDM4ELMNAHTT | |
| SCHEMBL7961327 | 0.79 | RAB9A (0.43) | HTR2AMCHR1LMNAHTT | |
| SCHEMBL8795290 | 0.73 | ALDH1A1 (0.41) | LMNA | |
| SCHEMBL7987248 | 0.73 | HRH3 (0.47) | KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7994413 | 0.72 | HCAR2 (0.41) | MAOB | |
| SCHEMBL7987765 | 0.70 | FFAR1 (0.40) | FFAR1FFAR4 | |
| SCHEMBL4383493 | 0.70 | CYP1A2 (0.33) | HTR2AMCHR1 | |
| SCHEMBL4382609 | 0.69 | HRH3 (0.56) | MAOBMAOAHTR2A | |
| SCHEMBL7972615 | 0.68 | HRH3 (0.37) | HTR2AMCHR1 | |
| SCHEMBL4384666 | 0.68 | LTA4H (0.33) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |