Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4383478 | 0.83 | CHRNB2 (0.47) | — | |
| SCHEMBL4387266 | 0.82 | CHRM5 (0.37) | DAOHSD17B10 | |
| SCHEMBL4385045 | 0.82 | L3MBTL1 (0.47) | HSD17B10 | |
| SCHEMBL7961327 | 0.82 | RAB9A (0.43) | — | |
| SCHEMBL4392060 | 0.81 | ALDH1A1 (0.49) | HSD17B10 | |
| SCHEMBL8795871 | 0.80 | GGPS1 (0.37) | — | |
| SCHEMBL7989019 | 0.80 | LMNA (0.54) | HSD17B10 | |
| SCHEMBL4381027 | 0.80 | MAOA (0.46) | MAOB | |
| SCHEMBL4394341 | 0.80 | MCL1 (0.37) | HSD17B10 | |
| SCHEMBL4379680 | 0.80 | KDM4E (0.49) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |