Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975824 | 1.00 | SGMS2 (0.52) | SGMS2KMT2AALDH1A1MEN1CYSLTR2 | |
| SCHEMBL7990641 | 1.00 | SGMS2 (0.52) | SGMS2KMT2AALDH1A1MEN1CYSLTR2 | |
| SCHEMBL7987324 | 0.83 | ALDH1A1 (0.47) | KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL7989643 | 0.79 | SGMS2 (0.50) | SGMS2KMT2AALDH1A1MEN1CNR2 | |
| SCHEMBL7990565 | 0.79 | SGMS2 (0.50) | SGMS2KMT2AALDH1A1MEN1CNR2 | |
| SCHEMBL10368444 | 0.77 | SGMS2 (0.50) | SGMS2KMT2AALDH1A1MEN1CNR2 | |
| SCHEMBL8817317 | 0.77 | SGMS2 (0.48) | SGMS2KMT2AALDH1A1MEN1PTGER1 | |
| SCHEMBL7975980 | 0.77 | SGMS2 (0.48) | SGMS2KMT2AALDH1A1MEN1PTGER1 | |
| SCHEMBL3099590 | 0.74 | FABP4 (0.57) | SGMS2ALDH1A1KDM4ETDP1PTGER1 | |
| SCHEMBL11603988 | 0.72 | MAPT (0.55) | SGMS2ALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207686-B1 | FOR THERAPY OF HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-0792265-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015109-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-23 | — | — | WO | disclosed |