Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973932 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1HPGDKMT2ABRD4 | |
| SCHEMBL7987962 | 0.80 | PDE4A (0.43) | SMN1; SMN2ALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL7975251 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1HPGDKMT2ABRD4 | |
| SCHEMBL7987958 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1HPGDKMT2ABRD4 | |
| SCHEMBL7987432 | 0.76 | HPGD (0.47) | SMN1; SMN2ALDH1A1HPGDKMT2ABRD4 | |
| SCHEMBL7984524 | 0.75 | HPGD (0.52) | SMN1; SMN2ALDH1A1HPGDKMT2ABRD4 | |
| SCHEMBL7988126 | 0.75 | HPGD (0.49) | SMN1; SMN2ALDH1A1HPGDKMT2ABRD4 | |
| SCHEMBL7985648 | 0.74 | HPGD (0.47) | SMN1; SMN2ALDH1A1HPGDKMT2ABRD4 | |
| SCHEMBL7984464 | 0.73 | ABCC8 (0.50) | SMN1; SMN2ALDH1A1HPGDKMT2ABRD4 | |
| SCHEMBL7987778 | 0.73 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1HPGDKMT2ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |