Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973934 | 0.81 | CYP11B1 (0.45) | ALDH1A1SMN1; SMN2HPGDGAAMET | |
| SCHEMBL7987968 | 0.80 | SMN1; SMN2 (0.43) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL7975252 | 0.78 | HPGD (0.45) | ALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL7988129 | 0.76 | MET (0.44) | ALDH1A1SMN1; SMN2HPGDGAAMET | |
| SCHEMBL7987434 | 0.75 | CYP11B1 (0.42) | ALDH1A1SMN1; SMN2HPGDMET | |
| SCHEMBL7984526 | 0.74 | MET (0.46) | ALDH1A1SMN1; SMN2HPGDMET | |
| SCHEMBL7985651 | 0.73 | CYP1A2 (0.41) | ALDH1A1SMN1; SMN2HPGDGAAMET | |
| SCHEMBL8059823 | 0.72 | MEN1 (0.45) | ALDH1A1SMN1; SMN2AGTR1AGTR2NR1H4 | |
| SCHEMBL7984468 | 0.72 | ABCC8 (0.46) | ALDH1A1SMN1; SMN2NR1H4HPGDMET | |
| SCHEMBL7987782 | 0.72 | NPC1 (0.44) | ALDH1A1SMN1; SMN2HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |