Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | CNOT7 | Q9UIV1 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986355 | 0.94 | SIGMAR1 (0.42) | ALDH1A1KDM4EMEN1LMNAMAPT | |
| SCHEMBL7984659 | 0.90 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1LMNAMAPT | |
| SCHEMBL7984406 | 0.89 | CASR (0.43) | ALDH1A1ADORA2AADORA3ADORA1CNOT7 | |
| Hydrochloric Acid SCHEMBL7987662 | 0.89 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1LMNAMAPT | |
| SCHEMBL7974615 | 0.89 | ADORA2A (0.44) | ALDH1A1ADORA2AADORA3ADORA1CNOT7 | |
| SCHEMBL7988551 | 0.87 | ADORA3 (0.43) | ALDH1A1KDM4EHPGDADORA2AADORA3 | |
| SCHEMBL7984683 | 0.87 | CNOT7 (0.37) | ALDH1A1ADORA2AADORA3ADORA1CNOT7 | |
| SCHEMBL7989009 | 0.84 | GAA (0.47) | ALDH1A1KDM4EMEN1LMNAMAPT | |
| SCHEMBL7992303 | 0.83 | CNOT7 (0.40) | KDM4ELMNAADORA2AADORA3ADORA1 | |
| SCHEMBL7991678 | 0.82 | HTT (0.40) | ALDH1A1KDM4EMEN1KMT2AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |