Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | CD38 | P28907 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29646334 | 0.83 | P2RX7 (0.58) | HDAC6HCRTR1HCRTR2P2RX7ALDH1A1 | |
| SCHEMBL1447540 | 0.83 | P2RX7 (0.58) | HDAC6HCRTR1HCRTR2P2RX7ALDH1A1 | |
| SCHEMBL4394779 | 0.83 | HDAC6 (0.51) | HDAC6LMNAPOLBHCRTR1HCRTR2 | |
| SCHEMBL4372942 | 0.83 | HDAC6 (0.51) | HDAC6LMNAPOLBGAAHCRTR1 | |
| SCHEMBL18033657 | 0.81 | HDAC6 (0.48) | HDAC6LMNAPOLBHCRTR1HCRTR2 | |
| SCHEMBL27764496 | 0.80 | HDAC6 (0.50) | HDAC6LMNAHCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL844529 | 0.80 | KDM4E (0.51) | HDAC6LMNAPOLBHCRTR1HCRTR2 | |
| SCHEMBL4384318 | 0.79 | HDAC6 (0.48) | HDAC6LMNAPOLBHCRTR1HCRTR2 | |
| SCHEMBL1568625 | 0.79 | HDAC6 (0.57) | HDAC6LMNAPOLBHCRTR1HCRTR2 | |
| SCHEMBL29488337 | 0.79 | NAPRT (0.58) | HDAC6LMNAHCRTR1HCRTR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110300522-A | For preventing and treating the composition that harmful microbe includes 1- (Phenoxy-pyridin base) -2- (1,2,4- triazol-1-yl)-alcohol derivative | 拜耳公司 | 2019-10-01 | — | — | CN | disclosed |
| CN-110267952-A | TRIAZOLETHIONE DERIVATIVES | 拜耳公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-109803965-A | The imidazolyl methyl dioxolane derivatives that 5- as fungicide replaces | 拜耳作物科学股份公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-108137538-A | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | 拜耳作物科学股份公司 | 2018-06-08 | — | — | CN | disclosed |
| US-8377923-B2 | Triazole derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2013-02-19 | — | — | US | disclosed |
| US-8377923-B2 | Triazole derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2013-02-19 | — | — | US | disclosed |
| US-20110105460-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-05-05 | — | — | US | disclosed |
| US-20110105460-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-05-05 | — | — | US | disclosed |
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105460-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | HSD11B1, HSD11B2, HSD3B1 | HDAC6 532/4885LMNA 4210/4885POLB 2414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.