Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393384 | 0.78 | NPBWR1 (0.51) | AMY1AMAPTMEN1KMT2ALMNA | |
| SCHEMBL7389163 | 0.78 | NPBWR1 (0.53) | AMY1AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7396372 | 0.76 | RAB9A (0.53) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7396880 | 0.76 | NPBWR1 (0.51) | AMY1AMAPTMEN1KMT2ANPBWR1 | |
| SCHEMBL7992209 | 0.74 | AMY1A (0.43) | AMY1AMAPTNPSR1MEN1KMT2A | |
| SCHEMBL7394125 | 0.72 | AMY1A (0.54) | AMY1AMAPTMEN1KMT2ALMNA | |
| SCHEMBL7392857 | 0.72 | RAB9A (0.49) | AMY1AMAPTNPSR1MEN1KMT2A | |
| SCHEMBL7388752 | 0.72 | KDM4E (0.46) | AMY1AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7392370 | 0.71 | AMY1A (0.46) | AMY1AALDH1A1KDM4ETDP1 | |
| SCHEMBL7388111 | 0.70 | AMY1A (0.66) | AMY1AMAPTNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066526-A1 | ESTER DERIVATIVES OF DIMETHYLPROPIONIC ACID AND PHARMACETUICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2001-09-13 | — | — | WO | disclosed |