Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977727 | 0.88 | RAF1 (0.55) | ALDH1A1LMNAPIN1RAF1PKN1 | |
| SCHEMBL7991753 | 0.85 | ALDH1A1 (0.43) | ALDH1A1LMNADHODHPIN1ERCC1 | |
| SCHEMBL7977930 | 0.82 | PIN1 (0.56) | ALDH1A1NPY5RDHODHPIN1ERCC1 | |
| SCHEMBL7988219 | 0.81 | TGFBR1 (0.47) | ALDH1A1LMNADHODHPIN1ERCC1 | |
| SCHEMBL7991975 | 0.77 | MAPK14 (0.49) | ALDH1A1RAF1KDM4EHPGDNPC1 | |
| SCHEMBL7995659 | 0.76 | GCGR (0.54) | RAF1 | |
| SCHEMBL7991767 | 0.76 | MAPK11 (0.57) | ALDH1A1LMNARAF1KDM4EHPGD | |
| SCHEMBL7989693 | 0.75 | MAPK14 (0.54) | ALDH1A1RAF1KDM4EHPGDCYP1A2 | |
| Hydrochloric Acid SCHEMBL7977803 | 0.75 | GCGR (0.53) | RAF1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7989739 | 0.74 | MAPK14 (0.56) | PIN1RAF1CYP1A2PARP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |