Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988219 | 0.87 | TGFBR1 (0.47) | ALDH1A1LMNADHODHGABRA1GABRG2 | |
| SCHEMBL7989683 | 0.85 | ALDH1A1 (0.48) | ALDH1A1LMNADHODHGABRA1GABRG2 | |
| SCHEMBL7988268 | 0.83 | PIN1 (0.52) | DHODHMETAP2PIN1ERCC1FEN1 | |
| SCHEMBL7977727 | 0.82 | RAF1 (0.55) | ALDH1A1LMNAPIN1RAF1 | |
| Hydrochloric Acid SCHEMBL7991931 | 0.74 | RAB9A (0.51) | LMNAMETAP2CYP1A2MAPK1 | |
| SCHEMBL7991975 | 0.72 | MAPK14 (0.49) | ALDH1A1RAF1 | |
| SCHEMBL7991767 | 0.71 | MAPK11 (0.57) | ALDH1A1LMNARAF1CYP1A2MAPK1 | |
| SCHEMBL7995659 | 0.71 | GCGR (0.54) | RAF1 | |
| SCHEMBL7989693 | 0.70 | MAPK14 (0.54) | ALDH1A1RAF1CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL7977803 | 0.70 | GCGR (0.53) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |