Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH1 | Q13686 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 9/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994013 | 0.80 | MAOB (0.54) | MAOBTDP1MAPT | |
| SCHEMBL7987092 | 0.78 | LTB4R (0.47) | MAOBLTB4RLTB4R2GAAPTGER1 | |
| SCHEMBL7993915 | 0.76 | ALKBH1 (0.38) | ALKBH1GAATP53MAPT | |
| SCHEMBL7990438 | 0.75 | EGLN1 (0.36) | ALKBH1GAA | |
| SCHEMBL2088184 | 0.73 | MAOB (0.68) | MAOBMAOA | |
| SCHEMBL2087289 | 0.73 | MAOB (0.70) | MAOBGAAMAOA | |
| SCHEMBL14818719 | 0.72 | LMNA (0.44) | GAATDP1 | |
| SCHEMBL19834602 | 0.71 | ACACA (0.60) | — | |
| SCHEMBL6239905 | 0.69 | KMT2A (0.52) | LTB4RLTB4R2GAA | |
| SCHEMBL31599495 | 0.67 | PIK3CA (0.40) | MAOBGAAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291530-B1 | Aryl-substituted acrylamides with Leukotriene B4 (LTB-4) receptor antagonist activity | NOVARTIS AG (CH) | 2001-09-18 | — | — | US | disclosed |
| EP-0942903-A1 | ARYL-SUBSTITUTED ACRYLAMIDES WITH LEUKOTRIENE B4 (LTB-4) RECEPTOR ANTAGONIST ACTIVITY | Novartis AG (CH) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998013347-A1 | ARYL-SUBSTITUTED ACRYLAMIDES WITH LEUKOTRIENE B4 (LTB-4) RECEPTOR ANTAGONIST ACTIVITY | NOVARTIS AG (CH) | 1998-04-02 | — | — | WO | disclosed |