Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976831 | 0.88 | FFAR1 (0.37) | MEN1KMT2AHRH3 | |
| SCHEMBL7991427 | 0.84 | HRH3 (0.37) | LMNAMAPTKDM4EL3MBTL1HRH3 | |
| SCHEMBL7991347 | 0.83 | MEN1 (0.48) | LMNAALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL7994316 | 0.81 | CXCR4 (0.38) | LMNAALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL7991433 | 0.80 | ALDH1A1 (0.43) | LMNAALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7988354 | 0.79 | SMN1; SMN2 (0.45) | MAPTHPGDSMN1; SMN2MEN1KMT2A | |
| Oxalic Acid SCHEMBL7990912 | 0.73 | MEN1 (0.47) | LMNAALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL7990787 | 0.73 | MCL1 (0.48) | LMNAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6861934 | 0.72 | HAO1 (0.34) | HRH3 | |
| SCHEMBL7991126 | 0.72 | HDAC4 (0.38) | LMNAMAPTHPGDSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | claimed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |