Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL6861930 | 0.73 | — | — | |
| Fumaric Acid SCHEMBL2878868 | 0.73 | — | — | |
| SCHEMBL7990915 | 0.72 | LMNA (0.42) | HRH3 | |
| SCHEMBL7976831 | 0.72 | FFAR1 (0.37) | KCNH2HRH3 | |
| SCHEMBL7991427 | 0.71 | HRH3 (0.37) | KCNH2HRH3 | |
| SCHEMBL7987317 | 0.69 | KCNH2 (0.39) | KCNH2HRH3 | |
| SCHEMBL7991433 | 0.68 | ALDH1A1 (0.43) | NPC1RAB9A | |
| SCHEMBL29331116 | 0.65 | HCAR2 (0.45) | HAO1MAOBRAB9A | |
| SCHEMBL22597090 | 0.65 | THRB (0.67) | — | |
| SCHEMBL7988354 | 0.64 | SMN1; SMN2 (0.45) | HRH3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416046-A1 | USE OF HISTAMINE RECEPTOR H3 GENE IN CONTROLLING BODY WEIGHT OR FOOD INTAKE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | EP | claimed |
| EP-1416046-A1 | USE OF HISTAMINE RECEPTOR H3 GENE IN CONTROLLING BODY WEIGHT OR FOOD INTAKE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | EP | disclosed |